Microbial Interaction Mechanisms and Networks in Complex Microbiomes
Duration of contract: 4 years
Planned starting date: ASAP
Place of work: Medical University of Graz
Main supervisor: Christine Moissl-Eichinger (CV | Lab Homepage)
Supervision team: David Berry, Holger Daims, Christina Kaiser
This position has been filled.
Project description:
The PhD student will investigate microbial interactions in the human small intestine microbiome (SI), using a combination of computational predictions and modellings and in situ experimental manipulations on SI microbiome microcosms and co-cultures.
In detail, metagenomic and amplicon data will be used for in silico network reconstruction and metabolic modelling. These data will be complemented by wet-lab experiments with multi-kingdom SI microbiomes and co-cultures using advanced stable isotope labeling and imaging techniques, metabolomics, proteomics and lipidomics, as well as real-time sequencing using Nanopore technique to observe microbial interactions under different conditions.
The PhD student will also interact with other team members who study the SI or environmental microbiomes. The ideal candidate is fascinated by microbial physiology and microbial interactions across domains. A strong interest in cutting-edge molecular and imaging approaches is required. An interest in and experience with bioinformatics analyses is ideal.